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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:30956
Term: trichloroacetic acid
Definition: A monocarboxylic acid that is acetic acid in which all three methyl hydrogens are substituted by chlorine.
Chemical ID: MESH:D014238
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3decreases cleavageEXP 6480464CTDTrichloroacetic Acid results in decreased cleavage of CASP3 proteinPMID:34794354
Casp3multiple interactionsEXP 6480464CTD[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in decreased cleavage of CASP3 protein]; diacerein inhibits the reaction [Trichloroacetic Acid results in decreased cleavage of CASP3 protein]PMID:34794354
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