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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:26216
Term: potassium atom
Definition: An alkali metal atom that has formula K.
Chemical ID: MESH:D011188
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityEXP 6480464CTDPotassium deficiency results in increased activity of CASP3 proteinPMID:11750908 PMID:12654341 PMID:14962062
Casp3multiple interactionsEXP 6480464CTD2-iodomelatonin inhibits the reaction [Potassium deficiency results in increased activity of CASP3 protein]; 4-phenyl-2-propionamidotetraline inhibits the reaction [2-iodomelatonin inhibits the reaction [Potassium deficiency results in increased activity of CASP3 protein]]; troglitazone inhibits the reaction [Potassium deficiency results in increased activity of CASP3 protein]PMID:11750908 PMID:14962062
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