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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2270
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Capns1
Name: calpain, small subunit 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Capns1decreases expressionISOCAPNS1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CAPNS1 proteinPMID:34186270
Capns1decreases expressionISOCapns1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of CAPNS1 mRNAPMID:33221593
Capns1increases expressionISOCAPNS1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of CAPNS1 mRNAPMID:29275510
Capns1multiple interactionsISOCAPNS1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of CAPNS1 genePMID:31601247
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