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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2228
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tspo
Name: translocator protein
Acc ID: CHEBI:145330
Term: 1-hydroxymidazolam
Definition: An imidazobenzodiazepine that is midazolam in which one of the hydrogens of the methyl group is substituted by a hydroxy group. It is the major metabolite of the anesthetic, midazolam.
Chemical ID: MESH:C040081
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tspoaffects bindingEXP 6480464CTD1-hydroxymethylmidazolam binds to TSPO protein; 1-hydroxymethylmidazolam metabolite binds to TSPO proteinPMID:7603229
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