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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2206
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bglap
Name: bone gamma-carboxyglutamate protein
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bglapdecreases expressionEXP 6480464CTDNicotine results in decreased expression of BGLAP mRNAPMID:29981921
Bglapdecreases expressionISOBGLAP (Homo sapiens)6480464CTDNicotine results in decreased expression of BGLAPPMID:19436947
Bglapincreases expressionISOBGLAP (Homo sapiens)6480464CTDNicotine results in increased expression of BGLAPPMID:19436947
Bglapmultiple interactionsISOBGLAP (Homo sapiens)6480464CTDTubocurarine inhibits the reaction [Nicotine results in increased expression of BGLAP]PMID:19436947
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