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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:9464
Term: testosterone enanthate
Definition: An enanthate ester that has formula C26H40O3.
Chemical ID: MESH:C004648
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxdecreases expressionEXP 6480464CTDtestosterone enanthate results in decreased expression of BAX mRNA; testosterone enanthate results in decreased expression of BAX proteinPMID:30154949 PMID:36015278
Baxmultiple interactionsEXP 6480464CTD2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in decreased expression of BAX mRNA]; cordycepin inhibits the reaction [testosterone enanthate results in decreased expression of BAX mRNA]; cordycepin inhibits the reaction [testosterone enanthate results in decreased expression of BAX protein]; Finasteride inhibits the reaction [testosterone enanthate results in decreased expression of BAX mRNA]; Finasteride inhibits the reaction [testosterone enanthate results in decreased expression of BAX protein]PMID:30154949 PMID:36015278
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