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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:76451
Term: alloxan
Definition: A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
Chemical ID: MESH:D000496
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDAlloxan results in increased expression of BAX proteinPMID:21982801 PMID:22138235 PMID:23092809
Baxmultiple interactionsEXP 6480464CTDTaurine inhibits the reaction [Alloxan results in increased expression of BAX protein]PMID:22138235 PMID:23092809
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