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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2186
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Avpr2
Name: arginine vasopressin receptor 2
Acc ID: CHEBI:5778
Term: hydrochlorothiazide
Definition: A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Chemical ID: MESH:D006852
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Avpr2decreases expressionEXP 6480464CTDHydrochlorothiazide results in decreased expression of AVPR2 mRNAPMID:17584643
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