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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2154
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arnt2
Name: aryl hydrocarbon receptor nuclear translocator 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arnt2affects expressionEXP 6480464CTDEstradiol affects the expression of ARNT2 mRNAPMID:24777823
Arnt2decreases expressionEXP 6480464CTDEstradiol results in decreased expression of ARNT2 mRNAPMID:22127542
Arnt2multiple interactionsEXP 6480464CTD11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol inhibits the reaction [Estradiol results in decreased expression of ARNT2 mRNA]; [Estradiol co-treated with Plant Preparations] results in decreased expression of ARNT2 mRNAPMID:22127542 PMID:26945725
Arnt2decreases expressionISOARNT2 (Homo sapiens)6480464CTDEstradiol results in decreased expression of ARNT2 mRNAPMID:16514628
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