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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2087
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family, member A1
Acc ID: CHEBI:80025
Term: Salinomycin
Definition: A spiroketal that has formula C42H70O11.
Chemical ID: MESH:C010327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1decreases expressionISOALDH1A1 (Homo sapiens)6480464CTDsalinomycin results in decreased expression of ALDH1A1 mRNA; salinomycin results in decreased expression of ALDH1A1 proteinPMID:25499043 PMID:30273566
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