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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:53444
Term: potassium dichromate
Definition: A potassium salt that is the dipotassium salt of dichromic acid.
Chemical ID: MESH:D011192
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1decreases phosphorylationEXP 6480464CTDPotassium Dichromate results in decreased phosphorylation of AKT1 proteinPMID:21262251
Akt1multiple interactionsEXP 6480464CTD[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased phosphorylation of AKT1 protein; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of AKT1 protein]PMID:21262251 PMID:35307491
Akt1increases expressionISOAKT1 (Homo sapiens)6480464CTDPotassium Dichromate results in increased expression of AKT1 proteinPMID:23718831
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