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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:28368
Term: novobiocin
Definition: A coumarin-derived antibiotic obtained from Streptomyces niveus.
Chemical ID: MESH:D009675
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1increases degradationISOAKT1 (Homo sapiens)6480464CTDNovobiocin analog results in increased degradation of AKT1 proteinPMID:20711301
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