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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:25942
Term: peroxynitrous acid
Definition: A nitrogen oxoacid that has formula HNO3.
Chemical ID: MESH:D030421
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1increases phosphorylationEXP 6480464CTDPeroxynitrous Acid results in increased phosphorylation of AKT1 proteinPMID:17302912
Akt1multiple interactionsEXP 6480464CTDBDNF protein promotes the reaction [Peroxynitrous Acid results in increased phosphorylation of AKT1 protein]; Catechin inhibits the reaction [Peroxynitrous Acid results in increased phosphorylation of AKT1 protein]; Peroxynitrous Acid promotes the reaction [BDNF protein results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [Peroxynitrous Acid results in increased phosphorylation of AKT1 protein]PMID:17302912
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