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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2053
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase 1
Acc ID: CHEBI:189929
Term: Maduramicin
Definition: null
Chemical ID: MESH:C018091
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases cleavageEXP 6480464CTDmaduramicin results in increased cleavage of PARP1 proteinPMID:29047155
Parp1multiple interactionsEXP 6480464CTDbenzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [maduramicin results in increased cleavage of PARP1 protein]PMID:29047155
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