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GENE - TERM ANNOTATION REPORT

RGD ID: 18918593
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Mpl
Name: MPL proto-oncogene, thrombopoietin receptor
Acc ID: DOID:2226
Term: myeloproliferative neoplasm
Definition: A myeloid neoplasm that is characterized by a group of slow growing blood cancers in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood. (DO)
Definition Source(s): http://www.bloodjournal.org/content/114/5/937.long "DO" "DO", http://www.cancer.gov/cancertopics/types/myeloproliferative "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mpl ISOMPL (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Myeloproliferative neoplasmPMID:14764528 PMID:18451306 PMID:18528423 PMID:19483125 PMID:19608689 PMID:20151976 PMID:21228032 PMID:23970983 PMID:25741868
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