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GENE - TERM ANNOTATION REPORT

RGD ID: 18361432
Species: Chlorocebus sabaeus
RGD Object: Gene
Symbol: TRPM4
Name: transient receptor potential cation channel subfamily M member 4
Acc ID: DOID:9000184
Term: Ventricular Fibrillation
Definition: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
Definition Source(s): MESH:D014693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TRPM4 ISOTRPM4 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Ventricular fibrillationPMID:21887725 PMID:25741868 PMID:26820365 PMID:28492532
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