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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1621551
Species: Mus musculus
RGD Object: Gene
Symbol: Pmaip1
Name: phorbol-12-myristate-13-acetate-induced protein 1
Acc ID: CHEBI:15365
Term: acetylsalicylic acid
Definition: A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Chemical ID: MESH:D001241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pmaip1increases expressionISOPMAIP1 (Homo sapiens)6480464CTDAspirin results in increased expression of PMAIP1 mRNA; Aspirin results in increased expression of PMAIP1 proteinPMID:15928584 PMID:19936928
Pmaip1increases response to substanceISOPMAIP1 (Homo sapiens)6480464CTDPMAIP1 results in increased susceptibility to AspirinPMID:19936928
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