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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606336
Species: Homo sapiens
RGD Object: Gene
Symbol: PDIA3
Name: protein disulfide isomerase family A member 3
Acc ID: CHEBI:10033
Term: warfarin
Definition: A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.
Chemical ID: MESH:D014859
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDIA3decreases expressionISOPdia3 (Mus musculus)6480464CTDWarfarin results in decreased expression of PDIA3 mRNAPMID:20493250
PDIA3increases expressionISOPdia3 (Mus musculus)6480464CTDWarfarin results in increased expression of PDIA3 mRNAPMID:20493250
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