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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605720
Species: Homo sapiens
RGD Object: Gene
Symbol: PTPN7
Name: protein tyrosine phosphatase non-receptor type 7
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTPN7decreases expressionISOPtpn7 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of PTPN7 mRNAPMID:25181051 PMID:34947998
PTPN7decreases methylationISOPtpn7 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of PTPN7 promoterPMID:27312807
PTPN7increases expressionISOPtpn7 (Mus musculus)6480464CTDbisphenol A results in increased expression of PTPN7 mRNAPMID:32156529
PTPN7increases methylationISOPtpn7 (Mus musculus)6480464CTDbisphenol A results in increased methylation of PTPN7 promoterPMID:27312807
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