Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605691
Species: Homo sapiens
RGD Object: Gene
Symbol: ACOT2
Name: acyl-CoA thioesterase 2
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACOT2increases expressionISOAcot2 (Mus musculus)6480464CTDClofibrate results in increased expression of ACOT2 mRNA; Clofibrate results in increased expression of ACOT2 proteinPMID:10787442 PMID:11330065 PMID:23811191 PMID:25270620 PMID:30629241 PMID:33549593
ACOT2increases expressionISOAcot2 (Rattus norvegicus)6480464CTDClofibrate results in increased expression of ACOT2 mRNA; Clofibrate results in increased expression of ACOT2 proteinPMID:16470657 PMID:18246545 PMID:27665778 PMID:32741897
ACOT2multiple interactionsISOAcot2 (Mus musculus)6480464CTDPPARA promotes the reaction [Clofibrate results in increased expression of ACOT2 mRNA]; PPARA promotes the reaction [Clofibrate results in increased expression of ACOT2 protein]PMID:10787442
Go Back to source page   Continue to Ontology report