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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605691
Species: Homo sapiens
RGD Object: Gene
Symbol: ACOT2
Name: acyl-CoA thioesterase 2
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACOT2multiple interactionsISOAcot2 (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACOT2 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACOT2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACOT2 mRNAPMID:17602206 PMID:20360939 PMID:22129741
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