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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605691
Species: Homo sapiens
RGD Object: Gene
Symbol: ACOT2
Name: acyl-CoA thioesterase 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACOT2increases expressionISOAcot2 (Mus musculus)6480464CTDpirinixic acid results in increased expression of ACOT2 mRNA; pirinixic acid results in increased expression of ACOT2 proteinPMID:15226431 PMID:16221962 PMID:16985257 PMID:17426115 PMID:18301758 PMID:18445702 PMID:20936131 PMID:23811191 PMID:25270620
ACOT2increases expressionISOAcot2 (Rattus norvegicus)6480464CTDpirinixic acid results in increased expression of ACOT2 mRNAPMID:12832660 PMID:19162173 PMID:22484513 PMID:26168851 PMID:27665778 PMID:32741897
ACOT2multiple interactionsISOAcot2 (Mus musculus)6480464CTDPPARA protein affects the reaction [pirinixic acid results in increased expression of ACOT2 mRNA]PMID:16221962
ACOT2multiple interactionsISOAcot2 (Rattus norvegicus)6480464CTDperfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of ACOT2 mRNA]PMID:26168851
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