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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1603392
Species: Homo sapiens
RGD Object: Gene
Symbol: INKA2
Name: inka box actin regulator 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
INKA2affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of INKA2 3' UTRPMID:27901495
INKA2increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of INKA2 mRNAPMID:20106945 PMID:21632981 PMID:22316170 PMID:26238291 PMID:32234424
INKA2increases expressionISOInka2 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of INKA2 mRNAPMID:32417428
INKA2multiple interactionsISOInka2 (Mus musculus)6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of INKA2 mRNAPMID:27858113
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