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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595844
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifitm3
Name: interferon induced transmembrane protein 3
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifitm3increases expressionISOIfitm3 (Mus musculus)6480464CTDDextran Sulfate results in increased expression of IFITM3 proteinPMID:32272095
Ifitm3multiple interactionsISOIfitm3 (Mus musculus)6480464CTD[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of IFITM3 mRNA; [Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of IFITM3 protein; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of IFITM3 protein]PMID:26271895 PMID:32272095
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