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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1594165
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gnb1l
Name: G protein subunit beta 1 like
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnb1laffects methylationISOGNB1L (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of GNB1L 5' UTR; Benzo(a)pyrene affects the methylation of GNB1L intronPMID:27901495 PMID:30157460
Gnb1ldecreases expressionISOGNB1L (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of GNB1L mRNAPMID:20064835 PMID:22316170 PMID:26238291
Gnb1lincreases expressionISOGnb1l (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of GNB1L mRNAPMID:19770486
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