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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589465
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl3
Name: BCL3, transcription coactivator
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl3decreases expressionEXP 6480464CTDEstradiol results in decreased expression of BCL3 mRNAPMID:32145629
Bcl3multiple interactionsEXP 6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of BCL3 mRNAPMID:32741896
Bcl3decreases expressionISOBCL3 (Homo sapiens)6480464CTDEstradiol results in decreased expression of BCL3 mRNAPMID:23373633
Bcl3increases expressionISOBCL3 (Homo sapiens)6480464CTDEstradiol results in increased expression of BCL3 mRNAPMID:31614463
Bcl3multiple interactionsISOBcl3 (Mus musculus)6480464CTDEstradiol inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA]PMID:12072388
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