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GENE - TERM ANNOTATION REPORT

RGD ID: 1586167
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tmem67
Name: transmembrane protein 67
Acc ID: DOID:8283
Term: peritonitis
Definition: A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output. (DO)
Definition Source(s): http://www.merck.com/mmpe/sec02/ch011/ch011b.html#sec02-ch011-ch011b-402 "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/001335.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tmem67 ISOTMEM67 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: PeritonitisPMID:19466712 PMID:19508969 PMID:19540516 PMID:19574260 PMID:20607301 PMID:21068128 PMID:21866095 PMID:23559409 PMID:25741868 PMID:26035863 PMID:26092869 PMID:28492532
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