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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1584013
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fpr2
Name: formyl peptide receptor 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fpr2affects expressionISOFpr2 (Mus musculus)6480464CTDBenzo(a)pyrene affects the expression of FPR2 mRNAPMID:22342234
Fpr2increases expressionISOFpr2 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of FPR2 mRNAPMID:22228805
Fpr2increases methylationISOFPR2 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of FPR2 5' UTR; Benzo(a)pyrene results in increased methylation of FPR2 promoterPMID:27901495
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