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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565739
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sgpp2
Name: sphingosine-1-phosphate phosphatase 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sgpp2increases methylationISOSgpp2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased methylation of SGPP2 genePMID:21212295
Sgpp2multiple interactionsISOSgpp2 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased methylation of SGPP2 genePMID:21212295
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