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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565646
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sox2
Name: SRY-box transcription factor 2
Acc ID: CHEBI:49639
Term: mercury dibromide
Definition: A mercury coordination entity composed of mercury and bromine with the formula HgBr2.
Chemical ID: MESH:C042720
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sox2decreases expressionISOSOX2 (Homo sapiens)6480464CTDmercuric bromide results in decreased expression of SOX2 mRNAPMID:26272509
Sox2multiple interactionsISOSOX2 (Homo sapiens)6480464CTD[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNAPMID:27188386
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