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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1564823
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xrcc2
Name: X-ray repair cross complementing 2
Acc ID: CHEBI:38960
Term: terbufos
Definition: An organothiophosphate insecticide that has formula C9H21O2PS3.
Chemical ID: MESH:C012568
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xrcc2decreases expressionISOXRCC2 (Homo sapiens)6480464CTDterbufos results in decreased expression of XRCC2 mRNA; terbufos results in decreased expression of XRCC2 proteinPMID:33221015
Xrcc2multiple interactionsISOXRCC2 (Homo sapiens)6480464CTD[terbufos co-treated with Fenthion] results in increased expression of XRCC2 mRNAPMID:33221015
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