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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1564821
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gnptab
Name: N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnptabaffects methylationISOGNPTAB (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of GNPTAB promoterPMID:27901495
Gnptabdecreases expressionISOGNPTAB (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of GNPTAB mRNAPMID:20064835
Gnptabdecreases methylationISOGnptab (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of GNPTAB intronPMID:27901495
Gnptabincreases expressionISOGnptab (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of GNPTAB mRNAPMID:22228805
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