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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563523
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dkkl1
Name: dickkopf like acrosomal protein 1
Acc ID: CHEBI:3763
Term: clorgyline
Definition: An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.
Chemical ID: MESH:D003010
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dkkl1increases expressionISODKKL1 (Homo sapiens)6480464CTDClorgyline results in increased expression of DKKL1 mRNAPMID:19691856
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