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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563014
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ncoa4
Name: nuclear receptor coactivator 4
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ncoa4multiple interactionsEXP 6480464CTD[lead acetate results in increased abundance of Lead] which results in increased expression of NCOA4 mRNA; [lead acetate results in increased abundance of Lead] which results in increased expression of NCOA4 protein; Deferoxamine inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NCOA4 mRNA]; Deferoxamine inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NCOA4 protein]; ferrostatin-1 inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NCOA4 mRNA]; ferrostatin-1 inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NCOA4 protein]PMID:39276841
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