Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1562895
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Hdac8
Name:	histone deacetylase 8

Acc ID:	CHEBI:9925
Term:	sodium valproate
Definition:	The sodium salt of valproic acid.

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Hdac8	decreases activity	EXP		9681716	RGD	Sodium valproate attenuates the reaction [deoxycorticosterone acetate increases activity of Hdac8 protein in the heart]

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.