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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557564
Species: Mus musculus
RGD Object: Gene
Symbol: Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Acc ID: CHEBI:5001
Term: fenofibrate
Definition: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Chemical ID: MESH:D011345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hectd1increases expressionEXP 6480464CTDFenofibrate results in increased expression of HECTD1 mRNAPMID:21318169
Hectd1multiple interactionsEXP 6480464CTD[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNAPMID:21318169
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