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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1556965
Species: Mus musculus
RGD Object: Gene
Symbol: Atg5
Name: autophagy related 5
Acc ID: CHEBI:173719
Term: Curcumol
Definition: null
Chemical ID: MESH:C022801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atg5multiple interactionsEXP 6480464CTDATG5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]]; ATG5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of CD34 protein]]; ATG5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR protein]]; ATG5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of PECAM1 protein]]; ATG5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of VEGFA protein]]; ATG5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of VWF protein]]PMID:33549628
Atg5multiple interactionsISOAtg5 (Rattus norvegicus)6480464CTD[ATG5 protein co-treated with curcumol] inhibits the reaction [VEGFA protein results in increased expression of ANGPT2 protein]; [ATG5 protein co-treated with curcumol] inhibits the reaction [VEGFA protein results in increased expression of HIF1A protein]; [ATG5 protein co-treated with curcumol] inhibits the reaction [VEGFA protein results in increased expression of PDGFBB protein]; ATG5 protein inhibits the reaction [curcumol inhibits the reaction [VEGFA protein results in increased expression of KLF5 mRNA]]; ATG5 protein inhibits the reaction [curcumol inhibits the reaction [VEGFA protein results in increased expression of KLF5 protein]]; curcumol inhibits the reaction [VEGFA protein results in increased expression of ATG5 mRNA]PMID:33549628
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