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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1556965
Species: Mus musculus
RGD Object: Gene
Symbol: Atg5
Name: autophagy related 5
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atg5multiple interactionsISOATG5 (Homo sapiens)6480464CTD[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein; ATG5 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein]PMID:25943029 PMID:36905866
Atg5multiple interactionsISOAtg5 (Rattus norvegicus)6480464CTDATG5 protein promotes the reaction [C1QTNF9 protein inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]PMID:32278738
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