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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553302
Species: Mus musculus
RGD Object: Gene
Symbol: Gnrh1
Name: gonadotropin releasing hormone 1
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnrh1decreases expressionEXP 6480464CTDperfluorooctane sulfonic acid results in decreased expression of GNRH1 proteinPMID:26358002
Gnrh1multiple interactionsEXP 6480464CTDEstrogens inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of GNRH1 protein]PMID:26358002
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