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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552970
Species: Mus musculus
RGD Object: Gene
Symbol: Gfra3
Name: glial cell line derived neurotrophic factor family receptor alpha 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gfra3affects expressionISOGfra3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of GFRA3 mRNAPMID:22298810
Gfra3decreases expressionISOGfra3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of GFRA3 mRNAPMID:21215274
Gfra3increases expressionISOGfra3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of GFRA3 mRNAPMID:34747641
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