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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552850
Species: Mus musculus
RGD Object: Gene
Symbol: Pgpep1
Name: pyroglutamyl-peptidase I
Acc ID: CHEBI:6121
Term: ketamine
Definition: A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Chemical ID: MESH:D007649
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgpep1decreases expressionISOPgpep1 (Rattus norvegicus)6480464CTDKetamine results in decreased expression of PGPEP1 mRNAPMID:20080153
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