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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552850
Species: Mus musculus
RGD Object: Gene
Symbol: Pgpep1
Name: pyroglutamyl-peptidase I
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgpep1decreases expressionEXP 6480464CTDTestosterone results in decreased expression of PGPEP1 mRNAPMID:20403060
Pgpep1increases expressionISOPGPEP1 (Homo sapiens)6480464CTDTestosterone results in increased expression of PGPEP1 mRNAPMID:21592394
Pgpep1multiple interactionsISOPGPEP1 (Homo sapiens)6480464CTD[Testosterone co-treated with Calcitriol] results in increased expression of PGPEP1 mRNAPMID:21592394
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