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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551470
Species: Mus musculus
RGD Object: Gene
Symbol: Rab27a
Name: RAB27A, member RAS oncogene family
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rab27aaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of RAB27A mRNAPMID:21570461
Rab27aincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of RAB27A mRNAPMID:15034205
Rab27amultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin affects the methylation of RAB27A intron] which results in decreased expression of RAB27A mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of RAB27A mRNAPMID:25975270 PMID:33017471
Rab27aaffects expressionISORab27a (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of RAB27A mRNAPMID:34747641
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