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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550772
Species: Mus musculus
RGD Object: Gene
Symbol: Slc1a5
Name: solute carrier family 1 (neutral amino acid transporter), member 5
Acc ID: CHEBI:10106
Term: zearalenone
Definition: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
Chemical ID: MESH:D015025
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc1a5decreases expressionISOSlc1a5 (Rattus norvegicus)6480464CTDZearalenone results in decreased expression of SLC1A5 mRNA; Zearalenone results in decreased expression of SLC1A5 proteinPMID:32858132
Slc1a5increases expressionISOSLC1A5 (Homo sapiens)6480464CTDZearalenone results in increased expression of SLC1A5 mRNAPMID:19371625
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