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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359638
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk9
Name: cyclin-dependent kinase 9
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk9increases phosphorylationISOCdk9 (Mus musculus)6480464CTDGlucose results in increased phosphorylation of CDK9 proteinPMID:33631230
Cdk9multiple interactionsISOCdk9 (Mus musculus)6480464CTD3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Glucose results in increased phosphorylation of CDK9 protein]; CDK9 protein affects the reaction [Glucose results in increased expression of COL4A4 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of IL1B mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of IL6 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of NOS2 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of TGFB1 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of TNF mRNA]; CDK9 protein affects the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; CDK9 protein affects the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; CDK9 protein affects the reaction [Glucose results in increased secretion of IL6 protein]; CDK9 protein affects the reaction [Glucose results in increased secretion of TNF protein]PMID:33631230
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