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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359143
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cct2
Name: chaperonin containing TCP1 subunit 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cct2increases expressionEXP 6480464CTDbisphenol A results in increased expression of CCT2 mRNAPMID:25181051
Cct2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of CCT2 genePMID:28505145
Cct2decreases expressionISOCCT2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CCT2 proteinPMID:34186270
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