Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1352729
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	TOP2A
Name:	DNA topoisomerase II alpha

Acc ID:	CHEBI:27871
Term:	chloroacetaldehyde
Definition:	Acetaldehyde substituted at C-2 by chlorine.
Chemical ID:	MESH:C004656

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
TOP2A	increases activity	EXP		6480464	CTD	chloroacetaldehyde results in increased activity of TOP2A protein	PMID:15751973

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.