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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351014
Species: Homo sapiens
RGD Object: Gene
Symbol: CTSD
Name: cathepsin D
Acc ID: CHEBI:47977
Term: 2-amino-2-deoxy-D-glucopyranose
Definition: A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTSDaffects localizationEXP 6480464CTDGlucosamine affects the localization of CTSD proteinPMID:15972124
CTSDdecreases expressionEXP 6480464CTDGlucosamine results in decreased expression of CTSD protein alternative formPMID:16850161
CTSDincreases activityEXP 6480464CTDGlucosamine results in increased activity of CTSD proteinPMID:16850161
CTSDmultiple interactionsEXP 6480464CTDpepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form]PMID:16850161
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