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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351014
Species: Homo sapiens
RGD Object: Gene
Symbol: CTSD
Name: cathepsin D
Acc ID: CHEBI:132893
Term: fangchinoline
Definition: A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from Stephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity.
Chemical ID: MESH:C060802
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTSDdecreases expressionEXP 6480464CTDfangchinoline results in decreased expression of CTSD proteinPMID:37689368
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