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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349499
Species: Homo sapiens
RGD Object: Gene
Symbol: UGT1A6
Name: UDP glucuronosyltransferase family 1 member A6
Acc ID: CHEBI:78886
Term: 2-tert-butylhydroquinone
Definition: A member of the class of hydroquinones in which one of the ring hydrogens of hydroquinone is replaced by a tert-butyl group.
Chemical ID: MESH:C018855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UGT1A6increases activityEXP 6480464CTD2-tert-butylhydroquinone results in increased activity of UGT1A6 proteinPMID:12948865
UGT1A6increases expressionEXP 6480464CTD2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNAPMID:10220484 PMID:12948865
UGT1A6multiple interactionsEXP 6480464CTDAHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]PMID:12948865
UGT1A6increases expressionISOUgt1a6 (Rattus norvegicus)6480464CTD2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNAPMID:12948865
UGT1A6multiple interactionsISOUgt1a6 (Rattus norvegicus)6480464CTDAHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of UGT1A6 mRNA]PMID:12948865
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